ABSTRACT
Background: Sexually transmitted infections (STIs) constitute a major health problem in the developing countries and prevalence of STIs varies from region to region in our country. Aim: To study the pattern and prevalence of sexually transmitted infections and HIV seropositivity among patients presenting in a tertiary care center. Materials and methods: A retrospective data was collected in the department of Dermatology at Shri Guru Ram Rai Institute of Medical and Health Sciences (SGRRIHMS), Shri Mahant Indiresh Hospital (SMIH), a tertiary care center in Dehradun, Uttarakhand, India, from January 2011 to December 2018. A total of 525 patients were analyzed in this study. Results: A total of 525 patients were enrolled in our study. STIs were more common in men, with male (365): female (160) ratio of 2.2:1. Maximum numbers of patients were in the age group of 25 to 34 years. Unskilled workers (22.28%) and housewives (20.00%) constituted major proportion. Majority of the cases presented with warts (38.09%) followed by molluscum contagiosum (20.95%) and herpes genitalis (19.61%). But herpes genitalis (27.39%) was found to be the most common STD seen among males and warts (68.75%) among the females. HIV seropositivity was seen among 20 (3.80%) patients and was most commonly associated with herpes genitalis infection (60.00%). Gunjan Gupta, Jitendra Singh Bist, Rahul Sudan, Kewal Krishan, Neeti Kumari. Clinicoepidemiological profile of sexually transmitted disease (STD) patients presenting in a tertiary care center. IAIM, 2019; 6(2): 7-12. Page 8 Conclusion: Increased prevalence of viral STDs like herpes genitalis, genital warts and mollascum contagiosum was seen in our study. Widespread use of antibacterial lead to falling trend of bacterial STDs.
ABSTRACT
Background: HIV infection is associated with numerous cutaneous changes even before the onset of immunologic dysfunction and AIDS. We all know that as search for reliable clinical indicators for management of human immunodeficiency syndrome in resource poor settings continues, cutaneous disorder can be a good clinical marker of HIV infection, underlying immune status and the disease progression. Aim and objectives: To study occurrence of various cutaneous manifestations in a patients infected with HIV. Materials and methods: 120 HIV positive patients above 14 year old with definite cutaneous manifestations attending dermatology OPD in Department of Skin, STD and Leprosy, in a tertiary care centre Dehradun were studied from December 2013 to January 2016. Results: Among 120 HIV positive patients in our cross-sectional study highest number of patients belonged to 31-40 years age group. Male to female ratio was 1.9: 1 and heterosexual route was the most common route of transmission. Among all cutaneous manifestations pruritic papular eruption, cutaneous drug reactions, molluscum contagiosum, seborrheic dermatitis were common. 14.17% had more than one cutaneous disorder and they had advanced stage of the disease. Conclusion: Early recognition of the cutaneous manifestation can help in better management of HIV infection in resource poor setting as it can indicate progression of the disease and underlying immune status
ABSTRACT
Background: Vitiligo is a common disorder causing depigmentation of the skin affecting patient’s quality of life. Various autoimmune disorders accompany vitiligo; this study was done to determine the prevalence of thyroid abnormality in children with vitiligo and compared with controls in this part of India. Materials and methods: Forty five children, suffering from non-segmental vitiligo, less than 16 years old and 60 healthy children were enrolled as cases and controls, respectively. Serum levels of Thyroid stimulating hormone (TSH), Free triodothyronine (fT3), Free thyroxine (fT4) and Anti-TPO antibody were accessed and compared with controls. Results: In both the groups, females outnumbered males. Thyroid function tests and thyroid autoantibodies abnormality were found in 15 (33.3%) cases. In controls, 8 (13.33%) children had increased TSH. The difference in both groups for thyroid function abnormality was significant (P= 0.0142). Conclusion: There is significant incidence of thyroid disease in children with vitiligo and hence they should be screened for thyroid function tests.
ABSTRACT
Background: Skin diseases are common in infancy. This study aimed to determine to prevalence of various dermatoses in infancy in Uttarakhand. Objectives: To determine the prevalence of different dermatologic diseases in infant in Uttarakhand. Methods: A prospective study was carried out for one year from 06 Sep 2013 to 05 Sep 2014, to study prevalence and patterns of dermatological lesions in infants, a tertiary care health facility in Uttarakhand. A total of 234 infants of both sexes were seen during this period. Results: Of 234 patients 58.9% were males. Noninfectious dermatitis was the largest group of skin disorders in infancy, constituting 35.89% of total cases. Seborrheic dermatitis was commonest type of non-infectious dermatitis in infancy (42.85%) followed by atopic dermatitis (19.04%), Ptyriasis alba (14.28 %), contact and diaper dermatitis (7.14% each). Seborrheic dermatitis did not display any gender or seasonal bias. Infectious/ parasitic infestations formed second largest group of dermatoses in infants (26.92%) with commonest being fungal infections (49% cases of infectious group) followed by parasitic infestations (26.98%). Bacterial and viral infections were formed only 12.69% and 11.11% of infectious group cases. Nonfungal and nonparasitic infections showed higher incidence in summers. Conclusion: Out of 234 infants who attended paediatric dermatology clinic, major dermatoses were of noninfectious origin with seborrheic dermatitis forming largest group. Infectious etiology dermatoses constituted second major group with fungal and parasitic etiology. Nonfungal and non-parasitic dermatoses showed higher prevalence in summer months.